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sRNA Annotations

2nd structure
(RNAfold)
sRNAG0020Get Sequence
Gene Name micA
Synonyms sraD;ECK2682;psrA10;b4442;
Position 2812824.....2812895
Length 72 bp
Strand forward
Gene Class MicA small RNA
Species Escherichia coli K12 MG1655
Evidence Inferred from direct assay;Inferred from mutant phenotype;
Source regulonDB

Genome position Promoter site

Structural RNA alignment
(RNALogo)
Get alignment sequences

Descriptions


    "micA is a small RNA that binds as an antisense RNA to the translation initiation region of ompA mRNA, blocking ribosome binding and downregulating OmpA expression. This downregulation requires the RNA-binding protein Hfq (Udekwu KI,2005). micA/sraD RNA is similar to sequences from Salmonella, Yersinia pestis and Klebsiella pneumoniae (Argaman L,2001). Regulation has been described (Argaman L,2001). The half life of sraD in stationary phase is 4 minutes (Vogel J,2003).".....

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References

Udekwu KI, Darfeuille F, Vogel J, Reimegård J, Holmqvist E, and Wagner EG (2005) "Hfq-dependent regulation of OmpA synthesis is mediated by an antisense RNA." Genes Dev 19 (19)  PubMed
Vogel J, Bartels V, Tang TH, Churakov G, Slagter-Jäger JG, Hüttenhofer A, and Wagner EG (2003) "RNomics in Escherichia coli detects new sRNA species and indicates parallel transcriptional output in bacteria." Nucleic Acids Res 31 (22)  PubMed
Argaman L, Hershberg R, Vogel J, Bejerano G, Wagner EG, Margalit H, and Altuvia S (2001) "Novel small RNA-encoding genes in the intergenic regions of Escherichia coli." Curr Biol 11 (12)  PubMed

Comparative Genomics by UCSC Genome Browser

Network Visualization

Regulators/sRNAs


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sRNAs/Targets


sRNA Expression Profiles

TitleF plasmid induced changes in expression levels in E. coli
Citation(s)16432259;16981998;SeriesGSE1154
Samples
1:MG1655_replicate12:MG1655_replicate23:MG1655F_replicate1
4:MG1655F_replicate25:DH5alpha_replicate16:DH5alpha_replicate2
7:DH5alphaF_replicate18:DH5alphaF_replicate2
IG_1755_2812176_2823854_fwd_f_st
more

External Database Connections

ECK120002578
EB4528
2847697
ABE-0047262
JWR0246
EG31156
G0-8866
b4442
RF00078


Department of Biological Science and Technology,

Institute of Bioinformatics National Chiao Tung University, Hsinchu, Taiwan

Contact with: bryan@mail.NCTU.edu.tw