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sRNA Annotations

2nd structure
(RNAfold)
sRNAG0073Get Sequence
Gene Name istR_1
Position 3851141.....3851215
Length 75 bp
Strand reverse
Gene Class IstR-1
Species Escherichia coli K12 MG1655
Evidence Inferred from experiment;
Source regulonDB

Genome position Promoter site

Structural RNA alignment
(RNALogo)
Get alignment sequences

Descriptions


            "The IstR-1 RNA is present throughout growth. It is able to base-pair with a short region of the tisAB mRNA, leading to RNase III-dependent cleavage of the message and thereby inactivating translation of the toxic TisB peptide. Induction of the SOS response causes depletion of the IstR-1 pool and thus causes accumulation of the tisAB mRNA, the TisB peptide, and slowing growth (Vogel J,2004)."
 

References

Vogel J, Argaman L, Wagner EG, and Altuvia S (2004) "The small RNA IstR inhibits synthesis of an SOS-induced toxic peptide." Curr Biol 14 (24)  PubMed

Comparative Genomics by UCSC Genome Browser

Network Visualization

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sRNAs/Targets


External Database Connections

ECK120015143
5061525
EG31167
G0-10202


Department of Biological Science and Technology,

Institute of Bioinformatics National Chiao Tung University, Hsinchu, Taiwan

Contact with: bryan@mail.NCTU.edu.tw