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sRNA Annotations

2nd structure
(RNAfold)
sRNAG0076Get Sequence
Gene Name ssrS
Synonyms ECK2906;b2911;ssr;
Position 3054005.....3054187
Length 183 bp
Strand forward
Gene Class 6S RNA
Species Escherichia coli K12 MG1655
Evidence Inferred from direct assay;
Source regulonDB

Genome position

NO conserved alignment determine the structure

Descriptions


    "The 6S RNA is involved in stationary phase regulation of transcription by the sigma70-holoenzyme (Wassarman KM,2000). The 6S RNA binds to both sigma70 and the beta/beta" subunits of core RNA polymerase and enables stable association between sigma70 and the core RNA polymerase (Wassarman KM,2000). During stationary phase, 6S RNA represses expression from a subset of sigma70-dependent promoters containing an extended -10 promoter element (Wassarman KM,2000. Kim EY,2004. Trotochaud AE,2004). 6S RNA also has an effect on the transcription o.....

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References

Wassarman KM, and Storz G (2000) "6S RNA regulates E. coli RNA polymerase activity." Cell 101 (6)  PubMed
Massé E, Majdalani N, and Gottesman S (2003) "Regulatory roles for small RNAs in bacteria." Curr Opin Microbiol 6 (2)  PubMed
Wassarman KM, Zhang A, and Storz G (1999) "Small RNAs in Escherichia coli." Trends Microbiol 7 (1)  PubMed
Hsu LM, Zagorski J, Wang Z, and Fournier MJ (1985) "Escherichia coli 6S RNA gene is part of a dual-function transcription unit." J Bacteriol 161 (3)  PubMed
Rice PW, and Dahlberg JE (1982) "A gene between polA and glnA retards growth of Escherichia coli when present in multiple copies: physiological effects of the gene for spot 42 RNA." J Bacteriol 152 (3)  PubMed
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Network Visualization

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sRNAs/Targets


sRNA Expression Profiles

TitleF plasmid induced changes in expression levels in E. coli
Citation(s)16432259;16981998;SeriesGSE1154
Samples
1:MG1655_replicate12:MG1655_replicate23:MG1655F_replicate1
4:MG1655F_replicate25:DH5alpha_replicate16:DH5alpha_replicate2
7:DH5alphaF_replicate18:DH5alphaF_replicate2
ssrS_b2911_st
more

External Database Connections

ECK120002541
EB4262
947405
ABE-0009556
JWR0067
EG30099
EG30099
b2911
332
RF00013


Department of Biological Science and Technology,

Institute of Bioinformatics National Chiao Tung University, Hsinchu, Taiwan

Contact with: bryan@mail.NCTU.edu.tw